INT273900

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
dorsal horn 1
Prkg2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 2 99.44 Very High Very High Very High
Lasting pain 11 93.36 High High
Dorsal horn 5 91.40 High High
Spinal cord 14 90.64 High High
hyperexcitability 11 90.04 High High
Neurotransmitter 3 54.32 Quite High
wide dynamic range 9 53.16 Quite High
Glutamate 2 52.96 Quite High
nMDA receptor 2 51.92 Quite High
Pain 9 46.60 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 99.44 Very High Very High Very High
Pain 20 93.36 High High
Hypersensitivity 21 84.60 Quite High
Nociception 5 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low
Unconsciousness 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of phosphorylated calcium/calmodulin-dependent protein kinase II (CaMKII) and ERK are two such regulators and these proteins have been shown to either engage rapamycin-sensitive pathways or synergise with them, leading to mRNA translation [20-22] and they are upregulated in the dorsal horn of the spinal cord after formalin injection into the hind paw [23].
Phosphorylation (phosphorylated) of protein kinase II in dorsal horn associated with dorsal horn and spinal cord
1) Confidence 0.05 Published 2009 Journal Mol Pain Section Body Doc Link PMC2699332 Disease Relevance 0.47 Pain Relevance 0.50

General Comments

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