INT273902

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mtor, Eif4ebp1) nucleus (Mtor, Eif4ebp1) mitochondrion (Mtor)
Golgi apparatus (Mtor) endoplasmic reticulum (Mtor) protein complex (Eif4ebp1)
Mtor (Rattus norvegicus)
Eif4ebp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dorsal horn 5 82.04 Quite High
Lasting pain 11 74.40 Quite High
hyperexcitability 11 63.28 Quite High
Central nervous system 1 36.00 Quite Low
Pain 9 30.40 Quite Low
c fibre 16 5.00 Very Low Very Low Very Low
Spinal cord 14 5.00 Very Low Very Low Very Low
wide dynamic range 9 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 99.00 Very High Very High Very High
Cancer 1 90.56 High High
Neurodegenerative Disease 1 89.68 High High
Disease 1 85.84 High High
Pain 20 73.52 Quite High
Injury 2 64.48 Quite High
Nervous System Injury 1 52.80 Quite High
Hypersensitivity 21 50.00 Quite Low
Nociception 5 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These pathways involve mTOR-dependent activation of the 70 kDa ribosomal protein S6 kinase (p70S6K) as well as the inactivation of the repressor of mRNA translation, eukaryotic initiation factor 4E (eIF4E) binding protein (4EBP) [1,2].
mTOR Positive_regulation (activation) of 4EBP
1) Confidence 0.50 Published 2009 Journal Mol Pain Section Body Doc Link PMC2699332 Disease Relevance 0.56 Pain Relevance 0.15

General Comments

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