INT273945

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh) extracellular region (Crh) nucleus (Crem)
DNA binding (Crem) response to stress (Crh) cytoplasm (Crh)
Anatomy Link Frequency
striatum 2
Crh (Mus musculus)
Crem (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 1 96.80 Very High Very High Very High
antagonist 3 95.88 Very High Very High Very High
agonist 1 95.24 Very High Very High Very High
amygdala 2 93.60 High High
antidepressant 4 93.36 High High
Hippocampus 5 89.56 High High
orphanin 2 84.48 Quite High
Dopamine 5 81.56 Quite High
Kinase C 1 70.88 Quite High
Nerve growth factor 1 66.32 Quite High
Disease Link Frequency Relevance Heat
Stress 11 99.74 Very High Very High Very High
Convulsion 10 92.84 High High
Shock 3 87.48 High High
Anxiety Disorder 12 60.72 Quite High
Targeted Disruption 24 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Epilepsy 6 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Status Epilepticus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Different types of stress, as well as CRH injections, increase ICER expression in a variety of neuroendocrine structures as well as in the striatum [12, 44–46].
CRH Positive_regulation (increase) of Gene_expression (expression) of ICER in striatum associated with stress
1) Confidence 0.20 Published 2009 Journal Mol Neurobiol Section Body Doc Link PMC2699388 Disease Relevance 0.52 Pain Relevance 0.43

General Comments

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