INT273953

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh) extracellular region (Crh) nucleus (Crem)
DNA binding (Crem) response to stress (Crh) cytoplasm (Crh)
Crem (Mus musculus)
Crh (Mus musculus)
Pain Link Frequency Relevance Heat
depression 3 96.56 Very High Very High Very High
Eae 7 89.16 High High
antidepressant 4 87.68 High High
Nucleus accumbens 5 82.84 Quite High
tricyclic antidepressant 1 48.56 Quite Low
Desipramine 2 41.76 Quite Low
Hippocampus 5 24.80 Low Low
Dopamine 5 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 11 99.68 Very High Very High Very High
Depression 3 96.56 Very High Very High Very High
Targeted Disruption 24 90.68 High High
Anxiety Disorder 12 80.68 Quite High
Convulsion 10 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Epilepsy 6 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Shock 3 5.00 Very Low Very Low Very Low
Status Epilepticus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stress induces ICER expression in different parts of the HPA axis, and ICER regulates transcription of the CRH gene during stress [24, 25, 45].
ICER Regulation (regulates) of Transcription (transcription) of CRH gene associated with stress
1) Confidence 0.26 Published 2009 Journal Mol Neurobiol Section Body Doc Link PMC2699388 Disease Relevance 0.99 Pain Relevance 0.27

General Comments

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