INT274016

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.27
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDE6A) signal transduction (PDE6A) plasma membrane (PDE6A)
Anatomy Link Frequency
retina 1
PDE6A (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 2 75.64 Quite High
backache 1 60.28 Quite High
nud 1 54.56 Quite High
ischemia 2 49.60 Quite Low
Angina 3 45.44 Quite Low
Spinal cord 2 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Onset of action 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 11 92.80 High High
Hypertension 9 90.04 High High
Coronary Artery Disease 2 89.36 High High
Increased Venous Pressure Under Development 3 76.40 Quite High
Headache 2 75.64 Quite High
Myocardial Infarction 3 73.76 Quite High
Hypersensitivity 1 64.40 Quite High
Arrhythmia Under Development 1 63.12 Quite High
Diarrhoea 1 62.32 Quite High
Vomiting 1 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Visual disturbances (blurred vision, flashing lights, blue haze, and change in color perception) occur due to weak inhibition of PDE6 in the retina.
Negative_regulation (inhibition) of PDE6 in retina
1) Confidence 0.03 Published 2006 Journal Clinical Interventions in Aging Section Body Doc Link PMC2699643 Disease Relevance 1.27 Pain Relevance 0.22

General Comments

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