INT274056

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.15
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CYP1A1) mitochondrion (CYP1A1) small molecule metabolic process (CYP1A1)
oxidoreductase activity (CYP1A1) endoplasmic reticulum (CYP1A1) enzyme binding (CYP1A1)
Anatomy Link Frequency
liver 1
CYP1A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 20 64.72 Quite High
antagonist 2 55.36 Quite High
antidepressant 2 43.20 Quite Low
Serotonin 4 12.88 Low Low
GABAergic 8 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Initiation And Maintenance Disorders 24 50.00 Quite Low
Disease 11 5.00 Very Low Very Low Very Low
Circadian Rhythm Sleep Disorders 6 5.00 Very Low Very Low Very Low
Sleep Disorders 5 5.00 Very Low Very Low Very Low
Depression 5 5.00 Very Low Very Low Very Low
Autoimmune Disease 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Pulmonary Disease 2 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The metabolism, studied in rat, monkey and human liver, showed degradation by CYP1A1, CYP1A2, CYP2D6, and CYP2C9, and also some conjugation with glucuronic acid.71,73 Most of the metabolites have only been partially characterized and are, again, nonhomologous to those of melatonin (Figure 1), for fundamental reasons.
Protein_catabolism (degradation) of CYP1A1 in liver
1) Confidence 0.15 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2699659 Disease Relevance 0 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox