INT274061

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGF, EGFR, TXK) extracellular space (EGF, EGFR) nucleus (EGFR, TXK)
cytoplasm (EGFR, TXK) signal transduction (EGF, EGFR) extracellular region (EGF, EGFR)
EGF (Homo sapiens)
EGFR (Homo sapiens)
TXK (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
Pain score 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 1 99.76 Very High Very High Very High
Cancer 7 96.56 Very High Very High Very High
Adhesions 1 76.40 Quite High
Apoptosis 2 73.12 Quite High
Solid Tumor 2 70.04 Quite High
Colon Cancer 17 67.32 Quite High
Pancreatic Cancer 6 66.16 Quite High
Non-small-cell Lung Cancer 12 65.36 Quite High
Metastasis 2 64.24 Quite High
Immunotherapy Of Cancer 1 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of EGFR by ligands, such as EGF, leads to receptor dimerization and activation of intrinsic tyrosine kinase (TK) activity.
EGF Positive_regulation (Activation) of EGFR Positive_regulation (activation) of tyrosine kinase
1) Confidence 0.06 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2699661 Disease Relevance 1.00 Pain Relevance 0

General Comments

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