INT274074

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.98
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map2k4) nucleus (Map2k4) kinase activity (Map2k4)
response to stress (Map2k4) cytoplasm (Map2k4)
Anatomy Link Frequency
retinas 1
neurons 1
Map2k4 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 38 98.88 Very High Very High Very High
Central nervous system 2 60.84 Quite High
anesthesia 2 47.28 Quite Low
ketamine 2 38.00 Quite Low
Disease Link Frequency Relevance Heat
Apoptosis 20 98.90 Very High Very High Very High
Cv Unclassified Under Development 36 98.88 Very High Very High Very High
Stress 46 98.64 Very High Very High Very High
Reperfusion Injury 12 98.52 Very High Very High Very High
Death 36 93.80 High High
Shock 2 71.56 Quite High
Ganglion Cysts 8 55.68 Quite High
Targeted Disruption 2 47.80 Quite Low
Injury 6 42.40 Quite Low
Body Weight 2 39.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, ASK1, SEK1/MEK4, and JNK is associated with damaged neurons after ischemia-reperfusion injury in rat retinas.


MEK4 Binding (associated) of in retinas associated with reperfusion injury and ischemia
1) Confidence 0.08 Published 2008 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2699777 Disease Relevance 1.29 Pain Relevance 0.23
, apoptosis signal-regulating kinase 1 (ASK1), SAPK/ERK kinase 1 (SEK1) and c-Jun N-terminal kinase (JNK) is associated with the damaged retinal neurons induced by ischemia-reperfusion injury.
SEK1 Binding (associated) of in neurons associated with reperfusion injury, ischemia and apoptosis
2) Confidence 0.08 Published 2008 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Abstract Doc Link PMC2699777 Disease Relevance 0.69 Pain Relevance 0.13

General Comments

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