INT274163

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.30
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cnp) plasma membrane (Cnp) intracellular (Cnp)
kinase activity (Cnp) cytoplasm (Cnp)
Cnp (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 132 96.36 Very High Very High Very High
Inflammatory response 14 87.20 High High
adenocard 8 85.84 High High
fibrosis 6 52.40 Quite High
cytokine 20 13.60 Low Low
corticosteroid 16 5.00 Very Low Very Low Very Low
metalloproteinase 12 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 94 99.38 Very High Very High Very High
INFLAMMATION 144 96.36 Very High Very High Very High
Pulmonary Disease 216 83.04 Quite High
Fibrosis 6 52.40 Quite High
Increased Venous Pressure Under Development 12 26.40 Quite Low
Occupational Lung Diseases 4 23.52 Low Low
Vomiting 26 5.00 Very Low Very Low Very Low
Nicotine Addiction 24 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Theophylline is believed to cause bronchodilation by inhibiting cyclic nucleotide phosphodiesterase (PDE), an enzyme that catalyzes the hydrolysis of cAMP and cyclic 3?
Negative_regulation (inhibiting) of cyclic nucleotide phosphodiesterase
1) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 0.48 Pain Relevance 0.19
Theophylline has long been used in treating asthma; it causes bronchodilation by inhibiting cyclic nucleotide phosphodiesterase (PDE), which inactivates cAMP.
Negative_regulation (inhibiting) of cyclic nucleotide phosphodiesterase associated with asthma
2) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Abstract Doc Link PMC2699952 Disease Relevance 0.82 Pain Relevance 0.24

General Comments

This test has worked.

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