INT274168

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.11
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Egf) plasma membrane (Egf)
Egf (Mus musculus)
Muc5ac (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 10 78.48 Quite High
Inflammatory response 7 78.40 Quite High
fibrosis 3 71.60 Quite High
Inflammation 66 54.76 Quite High
corticosteroid 8 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 47 98.80 Very High Very High Very High
Pulmonary Disease 108 98.24 Very High Very High Very High
Occupational Lung Diseases 2 88.40 High High
Fibrosis 3 87.76 High High
INFLAMMATION 72 78.40 Quite High
Hypersensitivity 3 67.16 Quite High
Disease Progression 1 42.68 Quite Low
Airway Remodeling 2 24.76 Low Low
Vomiting 13 5.00 Very Low Very Low Very Low
Nicotine Addiction 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At least in vitro, epidermal growth factor stimulates MUC5AC mRNA and protein expression; this can be reversed by PDE 4 inhibitors, which may contribute to their clinical efficacy in COPD and asthma (Mata et al 2005).
epidermal growth factor Positive_regulation (stimulates) of Gene_expression (expression) of MUC5AC mRNA associated with asthma and pulmonary disease
1) Confidence 0.01 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 2.11 Pain Relevance 0.17

General Comments

This test has worked.

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