INT27417

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Context Info
Confidence 0.04
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Aadac) lipid metabolic process (Aadac)
Aadac (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 10 97.56 Very High Very High Very High
Disease Link Frequency Relevance Heat
Death 2 98.54 Very High Very High Very High
Embryonal Carcinoma 1 97.32 Very High Very High Very High
Toxicity 1 82.20 Quite High
Exencephaly /

Neural Tube Defects

2 67.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When examined for cytotoxicity in F9 embryonal carcinoma cells, APAP and 7-OH-AAF each produced observable cell death only if reduced glutathione (GSH) had previously been depleted and if a deacetylase source were present; this cytotoxicity was also blocked by addition of paraoxon.
Gene_expression (source) of deacetylase associated with paracetamol, embryonal carcinoma and death
1) Confidence 0.04 Published 1989 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 2609350 Disease Relevance 0.36 Pain Relevance 0.63

General Comments

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