INT274172

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pde4a, TNF) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) nucleus (Pde4a)
Pde4a (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 89.76 High High
cytokine 10 72.76 Quite High
Inflammation 66 72.40 Quite High
antidepressant 1 58.72 Quite High
depression 2 47.96 Quite Low
Inflammatory response 7 7.52 Low Low
corticosteroid 8 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 97.56 Very High Very High Very High
Pulmonary Disease 108 97.28 Very High Very High Very High
INFLAMMATION 72 89.36 High High
Asthma 47 50.80 Quite High
Depression 2 47.96 Quite Low
Vomiting 13 5.00 Very Low Very Low Very Low
Nicotine Addiction 12 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PDE 4 inhibitors, including cilomilast and CI-1044, inhibit LPS-stimulated TNF-?
Negative_regulation (inhibitors) of PDE 4 Negative_regulation (inhibit) of Positive_regulation (stimulated) of TNF
1) Confidence 0.02 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699952 Disease Relevance 0.72 Pain Relevance 0.28

General Comments

This test has worked.

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