INT274185

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Context Info
Confidence 0.73
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.25
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ELN) extracellular region (ELN) proteinaceous extracellular matrix (ELN)
Anatomy Link Frequency
skin 2
extracellular matrix 1
alveolar walls 1
ELN (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 68.00 Quite High
Inflammation 18 67.60 Quite High
psoriasis 6 49.12 Quite Low
fibrosis 2 41.56 Quite Low
Piles 1 31.76 Quite Low
palliative 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wrinkles 4 97.44 Very High Very High Very High
Premature Aging 1 96.32 Very High Very High Very High
Decompression Sickness 2 93.12 High High
Burns 1 88.44 High High
Pressure And Volume Under Development 4 83.44 Quite High
Inflammatory Bowel Disease 6 79.48 Quite High
Erythema 1 78.72 Quite High
Disease 40 72.48 Quite High
INFLAMMATION 17 67.60 Quite High
Wound Healing 4 61.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antioxidants are effective in reducing free radical damage of collagen and elastin, the fibers that support the skin structure, and in preventing wrinkles and other signs of premature aging.[26]
Localization (damage) of elastin in skin associated with premature aging and wrinkles
1) Confidence 0.73 Published 2010 Journal Indian Journal of Dermatology Section Body Doc Link PMC2965901 Disease Relevance 0.66 Pain Relevance 0.10
In this study, the localization of lung elastin mRNA expression after pneumonectomy differed slightly from that observed in developing animals as in the latter case elastin mRNA expression was observed at the end and bend of alveolar walls but was not observed at the junctions of alveolar walls.
Localization (localization) of elastin mRNA in alveolar walls
2) Confidence 0.41 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699955 Disease Relevance 0.09 Pain Relevance 0
Pulmonary fibroblasts are the main cell type responsible for the synthesis and secretion of the main components of the alveolar extracellular matrix, proteoglycan, collagen and elastin.
Localization (secretion) of elastin in extracellular matrix
3) Confidence 0.36 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699955 Disease Relevance 0.06 Pain Relevance 0
Dermis, the inner layer of the skin, is composed of collagen, elastin and GAGs, which are created by fibroblasts.
Localization (created) of elastin in skin
4) Confidence 0.06 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2953398 Disease Relevance 0.44 Pain Relevance 0

General Comments

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