INT274208

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.15
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gsr) mitochondrion (Gsr) oxidoreductase activity (Gsr)
cytoplasm (Gsr)
Anatomy Link Frequency
neutrophils 4
granulocytes 2
lungs 2
Gsr (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 41 69.68 Quite High
Inflammation 103 68.32 Quite High
ischemia 6 50.00 Quite Low
cytokine 68 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 9 99.56 Very High Very High Very High
Mycobacterial Infection 290 97.40 Very High Very High Very High
Infection 267 96.72 Very High Very High Very High
Adhesions 15 92.72 High High
Granuloma 11 90.80 High High
Sprains And Strains 69 89.32 High High
Immunization 11 77.04 Quite High
INFLAMMATION 110 68.32 Quite High
Cryptococcus Infection 18 50.00 Quite Low
Cv Unclassified Under Development 6 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within the GR-1hi population, CD11b expression was not modified by the IR injury in either WT or MC3R-null animals; however, granulocytes from IR MC3R-null animals displayed an increased CD11b expression when compared with WT animals.
Neg (not) Positive_regulation (modified) of Gene_expression (expression) of GR-1hi in granulocytes associated with injury
1) Confidence 0.14 Published 2008 Journal FASEB J Section Body Doc Link PMC2700033 Disease Relevance 0.27 Pain Relevance 0
Together, these data suggest that the early recruitment of Gr1+ neutrophils may play a role in regulating the adaptive T cell immunity during M.tuberculosis infection.
Positive_regulation (recruitment) of Gene_expression (neutrophils) of Gr1 in neutrophils associated with mycobacterial infection and infection
2) Confidence 0.13 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020951 Disease Relevance 1.02 Pain Relevance 0.03
To our knowledge, this is the first study to experimentally show that the accumulation of Gr1+ neutrophils in the lungs takes place prior to accumulation of adaptive T cells.
Positive_regulation (accumulation) of Gene_expression (neutrophils) of Gr1 in lungs
3) Confidence 0.11 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020951 Disease Relevance 0.37 Pain Relevance 0
Our specific gating strategy for Gr-1+ cells concentrated on cells that expressed high levels of Gr-1 and were also CD11b+ and CD11c-, which are suggestive of neutrophils [46]–[49] (data not shown).
Positive_regulation (levels) of Gene_expression (expressed) of Gr-1 in neutrophils
4) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2731172 Disease Relevance 0.49 Pain Relevance 0.09

General Comments

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