INT274208
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Within the GR-1hi population, CD11b expression was not modified by the IR injury in either WT or MC3R-null animals; however, granulocytes from IR MC3R-null animals displayed an increased CD11b expression when compared with WT animals. | |||||||||||||||
| |||||||||||||||
|
Together, these data suggest that the early recruitment of Gr1+ neutrophils may play a role in regulating the adaptive T cell immunity during M.tuberculosis infection. | |||||||||||||||
| |||||||||||||||
|
To our knowledge, this is the first study to experimentally show that the accumulation of Gr1+ neutrophils in the lungs takes place prior to accumulation of adaptive T cells. | |||||||||||||||
| |||||||||||||||
|
Our specific gating strategy for Gr-1+ cells concentrated on cells that expressed high levels of Gr-1 and were also CD11b+ and CD11c-, which are suggestive of neutrophils [46][49] (data not shown). | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.