INT274227

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.96
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fasl) extracellular space (Fasl) extracellular region (Fasl)
cytoplasmic membrane-bounded vesicle (Fasl) plasma membrane (Fasl) lysosome (Fasl)
Anatomy Link Frequency
Mouse 2
T lymphocyte 2
Fasl (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 19 83.12 Quite High
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 83 99.52 Very High Very High Very High
Apoptosis 71 99.08 Very High Very High Very High
Lymphatic System Cancer 95 98.40 Very High Very High Very High
Death 29 89.60 High High
Thymoma 1 82.08 Quite High
Sprains And Strains 5 66.88 Quite High
T-cell Lymphoma 11 50.00 Quite Low
American Trypanosomiasis 12 49.68 Quite Low
Parasitemia 6 41.56 Quite Low
Disease 7 13.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blockade of FasL interaction partially increases CD4+ T lymphocyte recovery, in vitro and in vivo [51].
Negative_regulation (Blockade) of FasL Binding (interaction) of in T lymphocyte
1) Confidence 0.37 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2700264 Disease Relevance 0.84 Pain Relevance 0.08
Mouse Fas-Fc- a competitive inhibitor of Fas-Fas-L interactions effectively inhibited apoptosis in the lymphomas studied confirming the involvement of the Fas-Fas-L pathway in apoptosis induced by bacterial Sags.
Negative_regulation (inhibitor) of Fas-L Binding (interactions) of in Mouse associated with lymphatic system cancer and apoptosis
2) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 1.12 Pain Relevance 0

General Comments

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