INT274238

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 8.14
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (AIP) cytoplasm (AIP) signal transducer activity (AIP)
cytosol (AIP) signal transduction (AIP) nucleolus (AIP)
Anatomy Link Frequency
papilla 1
AIP (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 125 98.94 Very High Very High Very High
corticosteroid 14 96.48 Very High Very High Very High
Chronic pancreatitis 30 86.24 High High
imagery 26 76.12 Quite High
Inflammation 71 59.40 Quite High
Angina 2 34.56 Quite Low
Pain 6 14.32 Low Low
Bile 54 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 507 100.00 Very High Very High Very High
Interstitial Lung Diseases 23 100.00 Very High Very High Very High
Bronchiolitis Obliterans Organizing Pneumonia 109 99.84 Very High Very High Very High
Pancreatic Cancer 48 99.76 Very High Very High Very High
Lymphadenopathy 34 99.28 Very High Very High Very High
Fibrosis 91 98.94 Very High Very High Very High
Retroperitoneal Fibrosis 45 93.60 High High
Pressure And Volume Under Development 18 93.60 High High
Disease 132 90.68 High High
Respiratory Failure 1 90.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, a case of a 52-year-old man with retroperitoneal and mediastinal fibrosis who exhibited elevation of serum IgG4 levels in the absence of AIP was reported.14

Lymphadenopathy

Positive_regulation (absence) of AIP associated with fibrosis, lymphadenopathy and pancreatitis
1) Confidence 0.42 Published 2006 Journal J Gastroenterol Section Body Doc Link PMC2780632 Disease Relevance 2.07 Pain Relevance 0.29
We preliminarily reported that IgG4-immunostaining of biopsy specimens taken from the major duodenal papilla of AIP patients may support the diagnosis of AIP.76 Although improvement in clinical findings with steroid therapy may be useful in the differential diagnosis of AIP from pancreatic cancer, empiric administration of steroids should be avoided in order not to misdiagnose pancreatic cancer as AIP.
Positive_regulation (useful) of AIP in papilla associated with pancreatic cancer and pancreatitis
2) Confidence 0.42 Published 2006 Journal J Gastroenterol Section Body Doc Link PMC2780632 Disease Relevance 2.13 Pain Relevance 0.04
Reported AIP cases are increasing with the growing awareness of this entity around the world.


Positive_regulation (increasing) of AIP associated with pancreatitis
3) Confidence 0.39 Published 2006 Journal J Gastroenterol Section Body Doc Link PMC2780632 Disease Relevance 1.79 Pain Relevance 0.53
The rapidly progressive primary form of BOOP seems to have a better prognosis.[20–21] A rapidly progressive BOOP can be indistinguishable from acute interstitial pneumonitis (AIP) on clinical grounds.[23–25] Urgent tissue sampling may lead to urgent introduction of corticosteroids for primary BOOP, which might improve survival.[21]
Positive_regulation (indistinguishable) of AIP associated with bronchiolitis obliterans organizing pneumonia, interstitial lung diseases and corticosteroid
4) Confidence 0.18 Published 2008 Journal Annals of Thoracic Medicine Section Body Doc Link PMC2700454 Disease Relevance 2.15 Pain Relevance 0.11

General Comments

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