INT274379

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SERPINE1) extracellular region (SERPINE1) plasma membrane (SERPINE1)
Anatomy Link Frequency
blood 2
SERPINE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 1 97.62 Very High Very High Very High
tolerance 2 73.92 Quite High
Angina 3 72.96 Quite High
transdermal 15 68.08 Quite High
depression 13 5.00 Very Low Very Low Very Low
antidepressant 4 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
psychological dependence 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 3 97.62 Very High Very High Very High
Cardiovascular Disease 12 86.96 High High
Aging 24 74.96 Quite High
Cv General 3 Under Development 3 72.96 Quite High
Stroke 1 60.84 Quite High
Myocardial Infarction 2 60.52 Quite High
Anaemia 4 55.76 Quite High
Syndrome 2 48.20 Quite Low
Diabetes Mellitus 8 47.80 Quite Low
Impaired Glucose Tolerance 1 46.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The administration of T in physiological concentration increases coronary blood flow in patients with coronary heart disease.257 Beneficial effects on endothelial function258 and myocardial ischemia have also been demonstrated,248,259,260 but not with cardiovascular mortality.257,258 In addition, testosterone has a negative correlation with fibrinogen, plasminogen activator inhibitor-1261 and a direct effect on several vasoactive factors such as endothelin,262 prostacyclin, thromboxane A2 and platelet aggregation,263 blood coagulation, and fibrinolysis, respectively.248,261
Negative_regulation (negative) of activator inhibitor-1261 Neg (negative) Binding (correlation) of in blood associated with coronary artery disease and ischemia
1) Confidence 0.03 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2701485 Disease Relevance 0.91 Pain Relevance 0.33

General Comments

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