INT274404

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Context Info
Confidence 0.16
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Gata4) DNA binding (Gata4) transcription factor binding (Gata4)
cell-cell signaling (Gata4)
Anatomy Link Frequency
myocyte 1
Gata4 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 16 22.08 Low Low
imagery 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 89.20 High High
Ventricular Heart Septal Defects 7 88.00 High High
Stress 1 84.56 Quite High
Congenital Anomalies 1 81.60 Quite High
Embryonal Carcinoma 23 80.60 Quite High
Hyperplasia 2 73.92 Quite High
Dilated Cardiomyopathy 1 72.32 Quite High
Embryonic Lethality 3 66.68 Quite High
Natriuresis 3 62.16 Quite High
Heart Defects 2 36.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We established that the OTR-nitric oxide-cGMP pathway is essential for the OT-elicited differentiation of P19 stem cells into CM in association with elevation of transcription factors GATA-4 and myocyte-specific enhancer factor 2c (Mef2c) [12].
GATA-4 Binding (association) of in myocyte
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964328 Disease Relevance 0.35 Pain Relevance 0
In most cell and promoter contexts examined to date, FOG-2 functions as a transcriptional co-repressor by binding to the transcriptional activator GATA-4 and modulating GATA-dependent promoter activity [20], [21], [22].
GATA-4 Binding (binding) of
2) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.55 Pain Relevance 0

General Comments

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