INT274416

Context Info Confidence 0.16 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.54 Pain Relevance 0

Anatomy Link Frequency heart 1 Mir208a (Mus musculus)

Pain Link Frequency Relevance Heat anesthesia 1 5.00 isoflurane 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Congenital Anomalies 1 99.00 Stress 1 95.48 Dilated Cardiomyopathy 1 93.28 Embryonic Lethality 3 87.64 Disease 3 83.72 Ventricular Heart Septal Defects 7 43.84 Targeted Disruption 40 5.00 Repression 8 5.00 Cytomegalovirus Infection 7 5.00 Heart Defects 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

Targeted deletion of miR-208, while not leading to a developmental defect, blocked the heart's ability to develop a hypertrophic response to stress [16].

Localization (deletion) of miR-208 in heart associated with stress and congenital anomalies

1) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.54 Pain Relevance 0

General Comments

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