INT274420

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Zfpm2) intracellular (Zfpm2) DNA binding (Zfpm2)
nucleic acid binding transcription factor activity (Zfpm2) transcription factor binding (Zfpm2) cytoplasm (Zfpm2)
Anatomy Link Frequency
fibroblasts 4
Zfpm2 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 32 89.68 High High
Cytomegalovirus Infection 28 74.48 Quite High
Heart Defects 8 56.16 Quite High
Cv General 4 Under Development 4 47.28 Quite Low
Ventricular Heart Septal Defects 28 44.24 Quite Low
Targeted Disruption 160 21.04 Low Low
Embryonic Lethality 12 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Subacute Sclerosing Panencephalitis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
UTR, we co-transfected COS-7 fibroblasts with our miR-130a expression vector and our FOG-2 UTR reporter.
Positive_regulation (transfected) of Gene_expression (transfected) of FOG-2 UTR reporter in fibroblasts
1) Confidence 0.49 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.13 Pain Relevance 0
-O-methyl oligonucleotide to specifically block miR-130a and co-transfected it along with our FOG-2 3?
Positive_regulation (transfected) of Gene_expression (transfected) of FOG-2 3
2) Confidence 0.49 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.23 Pain Relevance 0
The results demonstrate that fibroblasts transfected with the FOG-2 3?
Positive_regulation (transfected) of Gene_expression (transfected) of FOG-2 3 in fibroblasts
3) Confidence 0.49 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.07 Pain Relevance 0
Though several factors may contribute to the dynamic pattern of FOG-2 protein expression during development, these results are consistent with the notion that miR-130a may play a role in regulating FOG-2 protein levels.


Spec (may) Positive_regulation (contribute) of Gene_expression (expression) of FOG-2 protein
4) Confidence 0.46 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.07 Pain Relevance 0

General Comments

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