INT274423

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Uts2r) plasma membrane (Uts2r) signal transducer activity (Uts2r)
Anatomy Link Frequency
neurons 2
fibroblasts 2
Uts2r (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 7 15.28 Low Low
cytokine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 59 95.68 Very High Very High Very High
Frailty 8 95.00 High High
Arrhythmias 2 Under Development 2 94.08 High High
Myotonia 14 92.96 High High
Cytomegalovirus Infection 7 73.20 Quite High
Disease 33 71.68 Quite High
Myotonic Dystrophy 22 50.00 Quite Low
Heart Defects 2 49.68 Quite Low
Cataract 7 43.96 Quite Low
Repression 9 41.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
UTR, we co-transfected COS-7 fibroblasts with our miR-130a expression vector and our FOG-2 UTR reporter.
Positive_regulation (transfected) of Gene_expression (transfected) of UTR in fibroblasts
1) Confidence 0.09 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2701631 Disease Relevance 0.07 Pain Relevance 0
What is the mechanism by which multiple copies of the normal 3’ UTR of DMPK cause DM1 phenotype?
Positive_regulation (cause) of Gene_expression (copies) of UTR
2) Confidence 0.08 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.51 Pain Relevance 0
Cortical neurons in culture were transfected with NLS-MS2-Venus, and an RNA localization reporter plasmid expressing BDNF-3'UTR fused to the binding sequence (MS2bs) of the bacteriophage MS2 protein.
Positive_regulation (transfected) of Gene_expression (expressing) of UTR in neurons
3) Confidence 0.05 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2889995 Disease Relevance 0 Pain Relevance 0

General Comments

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