INT274469

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.39
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL12A, IL6) extracellular region (IL12A, IL6) aging (IL6)
cytoplasm (IL12A)
Anatomy Link Frequency
lung 2
IL12A (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 3 63.52 Quite High
cytokine 12 54.04 Quite High
sodium channel 5 5.00 Very Low Very Low Very Low
cOX1 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 2 99.06 Very High Very High Very High
Lung Cancer 7 98.62 Very High Very High Very High
Carcinoma 4 94.12 High High
Adenocarcinoma 53 92.88 High High
Leukemia 1 85.00 Quite High
Lymphoproliferative Disease 1 83.68 Quite High
Cancer 63 80.08 Quite High
Death 2 74.08 Quite High
Non-small-cell Lung Cancer 18 67.44 Quite High
Severe Combined Immunodeficiency 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6 promotes lung cancer growth and metastasis [11], [13] and we [10] have demonstrated that IL-12 dampens IL-6 production in mouse splenocytes.
IL-12 Positive_regulation (dampens) of Gene_expression (production) of IL-6 in lung associated with lung cancer and metastasis
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2702099 Disease Relevance 1.39 Pain Relevance 0.06

General Comments

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