INT274578

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.55
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ABL1, PSTPIP1) cytosol (ABL1, PSTPIP1) mitochondrion (ABL1)
DNA binding (ABL1) signal transduction (PSTPIP1) protein modification process (ABL1)
Anatomy Link Frequency
SH3 2
ABL1 (Homo sapiens)
PSTPIP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 18 92.84 High High
Arthritis 4 57.48 Quite High
Pain 4 34.88 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 18 92.84 High High
Osteomyelitis 8 89.60 High High
Disease 20 60.28 Quite High
Acne 4 58.76 Quite High
Pyoderma Gangrenosum 4 58.36 Quite High
Arthritis 4 57.48 Quite High
Syndrome 18 56.36 Quite High
Pain 4 34.88 Quite Low
Fever 22 33.32 Quite Low
Adhesions 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PSTPIP1, but not PSTPIP2, also contains a C-terminal SH3 domain that is important for the binding of several PEST phosphatase substrates, including c-abl and WASP [8], [14].
c-abl Binding (binding) of PEST in SH3
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2702820 Disease Relevance 0.75 Pain Relevance 0.10
PSTPIP1, but not PSTPIP2, also contains a C-terminal SH3 domain that is important for the binding of several PEST phosphatase substrates, including c-abl and WASP [8], [14].
c-abl Binding (binding) of PSTPIP1 in SH3
2) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2702820 Disease Relevance 0.79 Pain Relevance 0.11

General Comments

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