INT274751

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 8
Disease Relevance 4.16
Pain Relevance 2.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 3
vesicles 1
syncytiotrophoblast 1
Mpeg1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 25 98.44 Very High Very High Very High
methadone 234 98.08 Very High Very High Very High
cocaine 96 97.16 Very High Very High Very High
Inflammation 85 96.52 Very High Very High Very High
Inflammatory response 20 79.36 Quite High
addiction 6 59.20 Quite High
opiate 12 58.80 Quite High
Abstinence syndrome 18 5.00 Very Low Very Low Very Low
Inflammatory marker 5 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 5 99.90 Very High Very High Very High
Cancer 5 98.78 Very High Very High Very High
Apoptosis 24 98.76 Very High Very High Very High
Malaria 350 98.44 Very High Very High Very High
Ovarian Cancer 25 98.10 Very High Very High Very High
Infection 120 97.40 Very High Very High Very High
Aging 10 97.12 Very High Very High Very High
INFLAMMATION 110 96.52 Very High Very High Very High
Communicable Diseases 5 95.72 Very High Very High Very High
Convalescence 5 86.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As virtually all cell types can release MPs, the presence of MPs of different origins circulating during acute P. vivax malaria is not unexpected.
Localization (release) of MPs associated with malaria
1) Confidence 0.05 Published 2010 Journal Malar J Section Body Doc Link PMC2998527 Disease Relevance 0.54 Pain Relevance 0.13
As MPs positive samples plasma from 12 patients, aging 45 to 65 years, diagnosed with ovarian carcinoma, as it has been shown that cancer cells from this highly lethal gynaecological malignancy can release MPs [22].


Localization (release) of MPs in plasma associated with malignant neoplastic disease, aging, cancer and ovarian cancer
2) Confidence 0.05 Published 2010 Journal Malar J Section Body Doc Link PMC2998527 Disease Relevance 1.12 Pain Relevance 0
To confirm if the absolute numbers of plasma MPs were different between malaria patients and healthy donors, as well as to determinate the numbers of plasma MPs per microliter (MPs/?
Localization (microliter) of MPs in plasma associated with malaria
3) Confidence 0.05 Published 2010 Journal Malar J Section Body Doc Link PMC2998527 Disease Relevance 0.21 Pain Relevance 0
Purification of MPs from plasma
Localization (Purification) of MPs in plasma
4) Confidence 0.05 Published 2010 Journal Malar J Section Body Doc Link PMC2998527 Disease Relevance 1.11 Pain Relevance 0
In the last few years, the study of microparticles (MPs) - submicron vesicles released from cells upon activation or apoptosis - has gained growing interest in the field of inflammation and in infectious diseases.
Localization (released) of MPs in vesicles associated with inflammation, communicable diseases and apoptosis
5) Confidence 0.05 Published 2010 Journal Malar J Section Abstract Doc Link PMC2998527 Disease Relevance 1.12 Pain Relevance 0.09
Microparticles (MPs) released from syncytiotrophoblast into maternal circuit increased by 30% after cocaine or heroin (P < 0.05) and the expression of P-glycoprotein in the tissue increased by ?
Localization (released) of MPs in syncytiotrophoblast associated with cocaine
6) Confidence 0.01 Published 2009 Journal Reprod Biol Endocrinol Section Abstract Doc Link PMC2703629 Disease Relevance 0.06 Pain Relevance 1.19
A non-significant reduction in the release of MPs (96 ± 7% of the the control) was observed when methadone was added.
Localization (release) of MPs associated with methadone
7) Confidence 0.01 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2703629 Disease Relevance 0 Pain Relevance 0.76
The concentration of the released microparticles (MPs) isolated from the maternal side after perfusion without addition of any drug (control) was 2190 ± 655 ng protein/g/min.
Localization (released) of MPs
8) Confidence 0.01 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2703629 Disease Relevance 0 Pain Relevance 0.74

General Comments

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