INT274832

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Dusp6, Tlr4) cell differentiation (Dusp6) cytosol (Dusp6)
signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
Anatomy Link Frequency
microglia 2
Dusp6 (Rattus norvegicus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 10 99.00 Very High Very High Very High
Cannabinoid 6 94.84 High High
Inflammation 21 50.00 Quite Low
Cannabinoid receptor 6 50.00 Quite Low
agonist 10 5.00 Very Low Very Low Very Low
Peripheral nerve injury 6 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Endocannabinoid 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 23 50.00 Quite Low
Nervous System Injury 9 5.00 Very Low Very Low Very Low
Neuropathic Pain 7 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The selective CBR2 antagonist, AM630, but not the CBR1 antagonist, AM281, significantly blocked the JWH015-induced MKP-3 in LPS stimulated microglia (1.12 ± 0.02 vs. 1.05 ± 0.02 of LPS alone group, LPS + JWH015 1 ?
MKP-3 Positive_regulation (stimulated) of Localization (group) of LPS in microglia associated with antagonist
1) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704199 Disease Relevance 0 Pain Relevance 0.19

General Comments

This test has worked.

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