INT274864

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.15
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Mapk1, TNF) nucleoplasm (Mapk1) mitochondrion (Mapk1)
intracellular (TNF) extracellular matrix organization (TNF) protein complex (Mapk1)
Mapk1 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 2 96.56 Very High Very High Very High
Peripheral nerve injury 6 96.16 Very High Very High Very High
allodynia 2 93.60 High High
Inflammation 21 76.88 Quite High
Cannabinoid receptor 6 56.32 Quite High
Cannabinoid 6 52.84 Quite High
Pain 3 42.04 Quite Low
chemokine 1 36.48 Quite Low
cytokine 2 36.00 Quite Low
Central nervous system 4 31.32 Quite Low
Disease Link Frequency Relevance Heat
Hypersensitivity 5 99.00 Very High Very High Very High
Diabetes Mellitus 1 98.00 Very High Very High Very High
Nervous System Injury 9 97.44 Very High Very High Very High
Frailty 2 96.84 Very High Very High Very High
Neuropathic Pain 7 93.60 High High
Drug Induced Neurotoxicity 1 86.36 High High
Necrosis 3 81.68 Quite High
Cancer 3 81.32 Quite High
INFLAMMATION 23 76.88 Quite High
Pain 5 42.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Microglial p-ERK inhibition reduces TNF production [21].
Negative_regulation (inhibition) of ERK Negative_regulation (reduces) of Gene_expression (production) of TNF
1) Confidence 0.05 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704199 Disease Relevance 1.15 Pain Relevance 0.41

General Comments

This test has worked.

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