INT274866

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Mapk1, TNF) nucleoplasm (Mapk1) mitochondrion (Mapk1)
intracellular (TNF) extracellular matrix organization (TNF) protein complex (Mapk1)
Mapk1 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropathic pain 4 91.24 High High
Inflammation 21 80.16 Quite High
cytokine 2 79.12 Quite High
dexamethasone 1 68.04 Quite High
cINOD 1 67.12 Quite High
Peripheral nerve injury 6 51.84 Quite High
Cannabinoid receptor 6 50.00 Quite Low
Antinociceptive 1 39.60 Quite Low
agonist 10 37.04 Quite Low
Pain 3 35.52 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 7 91.24 High High
INFLAMMATION 23 80.16 Quite High
Nervous System Injury 9 50.96 Quite High
Hypersensitivity 5 47.60 Quite Low
Alzheimer's Dementia 1 45.28 Quite Low
Pain 5 35.52 Quite Low
Necrosis 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Herein, we demonstrated that p-ERK is necessary for microglial TNF expression and migration.
ERK Positive_regulation (necessary) of Gene_expression (expression) of TNF
1) Confidence 0.06 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704199 Disease Relevance 0.35 Pain Relevance 0.33

General Comments

This test has worked.

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