INT274898

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.51
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lyn) Golgi apparatus (Lyn) plasma membrane (Lyn)
nucleus (Lyn) enzyme binding (Lyn) kinase activity (Lyn)
Anatomy Link Frequency
microglia 2
Lyn (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 11 99.60 Very High Very High Very High
Inflammation 12 97.24 Very High Very High Very High
IPN 5 97.04 Very High Very High Very High
Peripheral nerve injury 1 93.68 High High
allodynia 10 90.48 High High
Dorsal horn 1 88.76 High High
Brush evoked pain 15 79.48 Quite High
Lasting pain 11 62.80 Quite High
Dorsal horn neuron 2 61.28 Quite High
Spinal cord 1 43.56 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 38 99.60 Very High Very High Very High
INFLAMMATION 12 97.24 Very High Very High Very High
Inflammatory Pain 5 97.04 Very High Very High Very High
Nervous System Injury 19 93.68 High High
Hypersensitivity 6 71.16 Quite High
Pain 35 62.80 Quite High
Injury 5 30.88 Quite Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to the neuropathic pain model, neither the upregulation of P2X4R expression [7] nor activation of Lyn tyrosine kinase [13] has been demonstrated in spinal microglia following peripheral inflammation caused by CFA.
Neg (neither) Positive_regulation (upregulation) of Neg (nor) Positive_regulation (activation) of Lyn tyrosine kinase in microglia associated with inflammation and neuropathic pain
1) Confidence 0.35 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704200 Disease Relevance 1.51 Pain Relevance 1.05

General Comments

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