INT274924

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1) nucleus (Creb1) DNA binding (Creb1)
transcription factor binding (Creb1)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 84 99.88 Very High Very High Very High
c fibre 28 84.80 Quite High
spinal dorsal horn 50 62.28 Quite High
Dorsal horn neuron 1 50.00 Quite Low
nMDA receptor antagonist 3 29.32 Quite Low
Spinal cord 28 5.00 Very Low Very Low Very Low
Sciatic nerve 13 5.00 Very Low Very Low Very Low
nMDA receptor 7 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 8 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of CaMKII, ERK and CREB proteins and expression of c-Fos following HFS were prevented by either EphB2-Fc or targeted mutation of the EphB1 receptor
Positive_regulation (Activation) of Protein_catabolism (proteins) of CREB
1) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704201 Disease Relevance 0 Pain Relevance 0.39

General Comments

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