INT275094

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde5a) signal transduction (Pde5a)
Pde5a (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 53 100.00 Very High Very High Very High
Neurotransmitter 8 83.96 Quite High
Hippocampus 9 56.92 Quite High
depression 8 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
antidepressant 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 94 50.00 Quite Low
Targeted Disruption 15 5.00 Very Low Very Low Very Low
Anxiety Disorder 12 5.00 Very Low Very Low Very Low
Depression 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Schizophrenia 6 5.00 Very Low Very Low Very Low
Aging 6 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low
Vomiting 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As presynaptic cGMP plays a role in E-LTP, theoretically, inhibition of cGMP degradation with, for instance, a PDE9-I should, therefore, be able to influence L-LTP/LTM via E-LTP/STM as well.
cGMP Regulation (plays) of E-LTP associated with long-term potentiation
1) Confidence 0.05 Published 2008 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2704616 Disease Relevance 0 Pain Relevance 0.35

General Comments

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