INT275266

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 5.44
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf1a) extracellular space (Tnfrsf1a) extracellular region (Tnfrsf1a)
plasma membrane (Tnfrsf1a) nucleus (Tnfrsf1a) protein complex (Tnfrsf1a)
Anatomy Link Frequency
neurons 2
Tnfrsf1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 21 98.80 Very High Very High Very High
Hyperalgesia 8 96.00 Very High Very High Very High
dorsal root ganglion 50 92.96 High High
qutenza 61 73.44 Quite High
IPN 3 73.44 Quite High
analgesia 2 68.84 Quite High
rheumatoid arthritis 1 67.72 Quite High
Peripheral nervous system 1 53.32 Quite High
allodynia 1 33.04 Quite Low
Thermal hyperalgesia 2 32.04 Quite Low
Disease Link Frequency Relevance Heat
Cancer 29 99.80 Very High Very High Very High
Necrosis 8 99.56 Very High Very High Very High
INFLAMMATION 23 98.80 Very High Very High Very High
Apoptosis 165 98.60 Very High Very High Very High
Lymphatic System Cancer 285 97.96 Very High Very High Very High
Nervous System Injury 4 97.76 Very High Very High Very High
Hyperalgesia 10 96.00 Very High Very High Very High
Thymoma 3 94.48 High High
Ganglion Cysts 51 92.96 High High
Hypersensitivity 3 84.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure to specific bacterial Sags did not induced alterations in Bcl-2 expression or in the level of expression of TNFR1 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) (data not shown).
Neg (not) Regulation (alterations) of Gene_expression (expression) of TNFR1 associated with necrosis, cancer and apoptosis
1) Confidence 0.44 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 1.61 Pain Relevance 0
is released, and TNFR1 expression in neurons is increasing in proportion to the changes in TNF-?
Regulation (neurons) of Gene_expression (expression) of TNFR1 in neurons
2) Confidence 0.43 Published 2009 Journal Mol Pain Section Body Doc Link PMC2706230 Disease Relevance 1.17 Pain Relevance 0.80
Exposure to specific bacterial Sags did not induced alterations in Bcl-2 expression or in the level of expression of TNFR1 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) (data not shown).
Neg (not) Regulation (alterations) of Gene_expression (expression) of TNFR1 associated with necrosis, cancer and apoptosis
3) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 1.61 Pain Relevance 0
Whereas Sag exposure did not induce alterations in the expression of Bcl-2, TRAIL or TNFR1, interaction of Sags with the cognate V?
Neg (not) Regulation (alterations) of Gene_expression (expression) of TNFR1
4) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 1.05 Pain Relevance 0

General Comments

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