INT275284

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Context Info
Confidence 0.54
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tnfrsf1a, Trpv1) transport (Trpv1) protein complex (Tnfrsf1a)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1) cytosol (Trpv1)
Anatomy Link Frequency
neuronal 2
Tnfrsf1a (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 61 97.64 Very High Very High Very High
dorsal root ganglion 50 96.72 Very High Very High Very High
Neuropeptide 1 92.20 High High
Pain 6 70.68 Quite High
Inflammation 21 29.36 Quite Low
Hyperalgesia 8 26.56 Quite Low
antagonist 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
IPN 3 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 51 96.72 Very High Very High Very High
Targeted Disruption 10 95.08 Very High Very High Very High
Increased Venous Pressure Under Development 2 93.64 High High
Pain 6 70.68 Quite High
Hypersensitivity 3 40.24 Quite Low
INFLAMMATION 23 29.36 Quite Low
Nervous System Injury 4 28.32 Quite Low
Hyperalgesia 10 26.56 Quite Low
Nociception 7 5.00 Very Low Very Low Very Low
Inflammatory Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine further if ROS is involved in regulation of TNFR1 increases after TRPV1 activation, we also studied ROS production after TRPV1 activation by capsaicin in the mouse DRG neuronal cultures.
TNFR1 Positive_regulation (increases) of Gene_expression (activation) of TRPV1 in neuronal associated with dorsal root ganglion and qutenza
1) Confidence 0.54 Published 2009 Journal Mol Pain Section Body Doc Link PMC2706230 Disease Relevance 0.36 Pain Relevance 0.32

General Comments

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