INT275285

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ros1, Tnfrsf1a) plasma membrane (Ros1, Tnfrsf1a) cell differentiation (Ros1)
protein complex (Tnfrsf1a) cell proliferation (Ros1) extracellular space (Tnfrsf1a)
Anatomy Link Frequency
neurons 1
Ros1 (Mus musculus)
Tnfrsf1a (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 50 99.60 Very High Very High Very High
Pain 6 97.08 Very High Very High Very High
Inflammation 21 96.72 Very High Very High Very High
Neurotransmitter 1 92.28 High High
qutenza 61 84.00 Quite High
IPN 3 83.68 Quite High
Hyperalgesia 8 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 51 99.60 Very High Very High Very High
Pain 6 97.08 Very High Very High Very High
INFLAMMATION 23 96.72 Very High Very High Very High
Increased Venous Pressure Under Development 2 95.20 Very High Very High Very High
Inflammatory Pain 3 83.68 Quite High
Hypersensitivity 3 72.00 Quite High
Targeted Disruption 10 54.00 Quite High
Hyperalgesia 10 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study reveals that TRPV1 activation increases ROS which act as signaling molecules to increase TNFR1 in mouse DRG neurons.
ROS Positive_regulation (increase) of TNFR1 in neurons associated with dorsal root ganglion
1) Confidence 0.27 Published 2009 Journal Mol Pain Section Body Doc Link PMC2706230 Disease Relevance 1.06 Pain Relevance 0.72

General Comments

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