INT275288

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Trpv1, Ros1) cell differentiation (Ros1) transport (Trpv1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1) cytosol (Trpv1)
Anatomy Link Frequency
neurons 2
Trpv1 (Mus musculus)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 61 100.00 Very High Very High Very High
dorsal root ganglion 50 99.58 Very High Very High Very High
Inflammation 21 97.36 Very High Very High Very High
Neurotransmitter 1 73.04 Quite High
Pain 6 62.48 Quite High
IPN 3 35.68 Quite Low
Neuropeptide 1 6.12 Low Low
Hyperalgesia 8 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 51 99.58 Very High Very High Very High
INFLAMMATION 23 97.36 Very High Very High Very High
Hypersensitivity 3 95.72 Very High Very High Very High
Increased Venous Pressure Under Development 2 67.04 Quite High
Pain 6 62.48 Quite High
Inflammatory Pain 3 35.68 Quite Low
Targeted Disruption 10 9.00 Low Low
Hyperalgesia 10 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While much work has been done in vivo in rat, our work in cultured mouse DRG neurons challenging TRPV1 with capsaicin to increase ROS production is similar to in vivo microenvironment conditions present during inflammation.
TRPV1 Positive_regulation (increase) of Gene_expression (production) of ROS in neurons associated with dorsal root ganglion, inflammation and qutenza
1) Confidence 0.21 Published 2009 Journal Mol Pain Section Body Doc Link PMC2706230 Disease Relevance 0.70 Pain Relevance 0.71

General Comments

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