INT275319

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gpr143) Golgi apparatus (Gpr143) plasma membrane (Gpr143)
lysosome (Gpr143) signal transducer activity (Gpr143)
Anatomy Link Frequency
cartilage 1
Tg(Ngf)47Kma (Mus musculus)
Gpr143 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 31 100.00 Very High Very High Very High
metalloproteinase 14 94.44 High High
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 31 100.00 Very High Very High Very High
Injury 43 84.88 Quite High
Sprains And Strains 21 72.84 Quite High
Apoptosis 14 11.00 Low Low
Patellar Dislocation 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Joint Instability 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, ADAMTS-5 has been identified as the main aggrecanase in mouse cartilage and its ablation protected the mice from OA induced by DMM47.
DMM47 Positive_regulation (induced) of OA in cartilage associated with osteoarthritis
1) Confidence 0.00 Published 2009 Journal Osteoarthritis Cartilage Section Body Doc Link PMC2706394 Disease Relevance 0.59 Pain Relevance 0.17

General Comments

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