INT275338

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.14
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gfm1) intracellular (Gfm1) translation (Gfm1)
GTPase activity (Gfm1)
Anatomy Link Frequency
diaphragm 4
astrocytes 2
EDL 2
Gfm1 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 14 95.40 Very High Very High Very High
adenocard 3 81.36 Quite High
ischemia 9 68.08 Quite High
imagery 15 5.00 Very Low Very Low Very Low
corticosteroid 9 5.00 Very Low Very Low Very Low
anesthesia 8 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
isoflurane 5 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Thoracotomy 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alcoholic Cardiomyopathy 5 99.28 Very High Very High Very High
Pulmonary Disease 42 99.24 Very High Very High Very High
Pressure And Volume Under Development 50 97.48 Very High Very High Very High
Targeted Disruption 8 92.20 High High
Coronary Heart Disease 9 90.04 High High
Apoptosis 41 88.36 High High
Fatigue 6 87.12 High High
Alcohol Addiction 2 82.68 Quite High
Infarction 10 81.68 Quite High
Respiratory Failure 30 80.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consequently, enhancing mitochondrial metabolism in astrocytes is a relatively unexplored strategy to decrease edema and preserve the penumbra [13].
Positive_regulation (enhancing) of Gene_expression (metabolism) of mitochondrial in astrocytes associated with pressure and volume under development
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008710 Disease Relevance 1.11 Pain Relevance 0.03
Myocardial mitochondrial damage was assessed using mitochondrial superoxide (O2•?)
Positive_regulation (assessed) of Gene_expression (damage) of mitochondrial
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2807457 Disease Relevance 0.94 Pain Relevance 0.08
This is in agreement with the results of Saborido et al (1991), who found that in rat extensor digitorum longus (EDL), but not in soleus muscle, mitochondrial function was enhanced after treatment with fluoxymesterone and meth-androstanolone, suggesting a higher sensitivity for anabolic steroid in fast-twitch (EDL) muscle.
Positive_regulation (enhanced) of Neg (not) Gene_expression (function) of mitochondrial in EDL
3) Confidence 0.02 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2706598 Disease Relevance 0 Pain Relevance 0.04
Mitochondrial function is enhanced in the diaphragm of patients with COPD (Ribera et al 2002), as indicated by increases in the maximum rate of mitochondrial respiration and efficiency of the mitochondrial electron transport chain.
Positive_regulation (increases) of Gene_expression (respiration) of mitochondrial in diaphragm associated with pulmonary disease
4) Confidence 0.02 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2706598 Disease Relevance 0.56 Pain Relevance 0
Mitochondrial function is enhanced in the diaphragm of patients with COPD (Ribera et al 2002), as indicated by increases in the maximum rate of mitochondrial respiration and efficiency of the mitochondrial electron transport chain.
Positive_regulation (increases) of Gene_expression (respiration) of mitochondrial in diaphragm associated with pulmonary disease
5) Confidence 0.02 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2706598 Disease Relevance 0.54 Pain Relevance 0

General Comments

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