INT27536

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Context Info
Confidence 0.52
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.41
Pain Relevance 1.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
CPA 1
sympathetic nervous system 1
Caf (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 4 100.00 Very High Very High Very High
cytokine 12 99.98 Very High Very High Very High
Locus ceruleus 348 98.44 Very High Very High Very High
antagonist 26 89.72 High High
adenocard 5 88.92 High High
Clonidine 38 82.24 Quite High
cocaine 6 62.24 Quite High
Dopamine 11 57.20 Quite High
noradrenaline 57 43.68 Quite Low
Codeine 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Death 2 99.96 Very High Very High Very High
Immunization 20 90.80 High High
Mycobacterial Infection 48 63.20 Quite High
Pressure Volume 2 Under Development 1 38.64 Quite Low
Miosis 8 32.64 Quite Low
Ehlers-danlos Syndrome 2 27.60 Quite Low
Sleep Disorders 15 27.04 Quite Low
Idiopathic Hypersomnolence 1 17.36 Low Low
Apnoea 1 12.24 Low Low
Demyelinating Disease 1 9.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, combined administration of 4 drugs and MEPH + CAF + CPA at the doses equivalent to those contained in 40ml/kg of BRON produced death of 1 or 2 mice out of 10-14.
Gene_expression (produced) of CAF in CPA associated with death
1) Confidence 0.52 Published 1989 Journal Arukoru Kenkyuto Yakubutsu Ison Section Abstract Doc Link 2624570 Disease Relevance 0.10 Pain Relevance 0
In the case of CRS model, A1(1) (1%, 1 cm) were used to obtain three linear equation functions and this linear equation system was resolved by the Cramer's rule for the prediction of PAR, CAF and ASP in samples.
Gene_expression (prediction) of CAF associated with paracetamol
2) Confidence 0.36 Published 2005 Journal Chem. Pharm. Bull. Section Abstract Doc Link 16079516 Disease Relevance 0 Pain Relevance 0.30
cytokine production of Ag:CAF01:Bioneedle as compared to Ag:CAF01 (Figure 1B).
Gene_expression (production) of CAF01 associated with cytokine
3) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993957 Disease Relevance 0.15 Pain Relevance 0.05
cytokine production of Ag:CAF01:Bioneedle as compared to Ag:CAF01 (Figure 1B).
Gene_expression (production) of CAF01 associated with cytokine
4) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993957 Disease Relevance 0.15 Pain Relevance 0.05
Administration of caffeine also produces increases in heart rate [194], blood pressure [194, 315, 464] and temperature [229], consistent with activation of the sympathetic nervous system.
Gene_expression (produces) of caffeine in sympathetic nervous system
5) Confidence 0.01 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687931 Disease Relevance 0 Pain Relevance 0.73

General Comments

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