INT275374

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.35
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (JUN, NDRG1) nucleus (JUN, NDRG1) nucleoplasm (JUN)
nuclear chromosome (JUN) aging (JUN) DNA binding (JUN)
JUN (Homo sapiens)
NDRG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 17 70.72 Quite High
Thermal hyperalgesia 1 57.08 Quite High
Peripheral nerve injury 3 52.28 Quite High
calcitonin gene related peptide 6 49.28 Quite Low
Inflammatory mediators 1 33.32 Quite Low
Inflammatory response 1 24.00 Low Low
cytokine 1 18.24 Low Low
Inflammation 1 17.84 Low Low
Neuropathic pain 20 5.84 Low Low
Sciatic nerve 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 9 98.96 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 109 97.60 Very High Very High Very High
Nervous System Injury 8 93.68 High High
Injury 10 81.80 Quite High
Neuropathy 10 77.44 Quite High
Neuropathic Pain 34 75.04 Quite High
Pain 12 70.72 Quite High
Hyperalgesia 1 57.08 Quite High
Congenital Anomalies 2 36.08 Quite Low
INFLAMMATION 3 32.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that caspase-3, but not p-c-Jun, increased in the DRG suggesting that specific apoptotic pathways are induced by HIV-1 gp120.
p-c-Jun Positive_regulation (increased) of DRG associated with acquired immune deficiency syndrome or hiv infection and apoptosis
1) Confidence 0.00 Published 2007 Journal Pain Section Body Doc Link PMC2706950 Disease Relevance 1.35 Pain Relevance 0.15

General Comments

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