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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.73
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ERVW-1, Cxcr4) endosome (Cxcr4) cytoplasmic membrane-bounded vesicle (Cxcr4)
signal transducer activity (Cxcr4)
Anatomy Link Frequency
neurons 1
ERVW-1 (Homo sapiens)
Cxcr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 3 100.00 Very High Very High Very High
Central nervous system 5 94.16 High High
unmyelinated 4 86.12 High High
Pain 17 79.92 Quite High
intrathecal 1 75.92 Quite High
Peripheral nervous system 1 68.88 Quite High
Stimulus evoked pain 1 58.92 Quite High
Neuropathic pain 20 48.12 Quite Low
Sciatic nerve 18 5.00 Very Low Very Low Very Low
Analgesic 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 109 98.98 Very High Very High Very High
Infection 4 96.86 Very High Very High Very High
Apoptosis 9 95.84 Very High Very High Very High
Neuropathy 10 80.32 Quite High
Pain 12 79.92 Quite High
Disease 3 67.92 Quite High
Congenital Anomalies 2 56.08 Quite High
Toxicity 1 51.36 Quite High
Neuropathic Pain 34 48.12 Quite Low
Hypersensitivity 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Direct infection of the nervous system by HIV is thought to be unlikely (Michaels et al., 1988; Lipton, 1998) instead, HIV-1 appears to interact indirectly with neurons via binding of the external envelope protein, gp120, to the chemokine receptors CXCR4 and/or CCR5.
external envelope protein Binding (binding) of CXCR4 in neurons associated with chemokine, acquired immune deficiency syndrome or hiv infection and infection
1) Confidence 0.00 Published 2007 Journal Pain Section Body Doc Link PMC2706950 Disease Relevance 1.73 Pain Relevance 0.46

General Comments

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