INT275461

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Atxn1, Atxn2) cytoplasm (Atxn1, Atxn2) nucleoplasm (Atxn1)
Golgi apparatus (Atxn2) RNA binding (Atxn1)
Atxn1 (Mus musculus)
Atxn2 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 26 84.72 Quite High
amygdala 21 67.80 Quite High
Hippocampus 12 42.32 Quite Low
Pain 3 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 20 98.36 Very High Very High Very High
Anxiety Disorder 47 94.00 High High
Sprains And Strains 1 87.12 High High
Appetite Loss 13 85.52 High High
Spinocerebellar Ataxia Type 2 11 82.48 Quite High
Attention Deficit Hyperactivity Disorder 3 35.60 Quite Low
Cognitive Disorder 2 26.72 Quite Low
Hyperphagia 2 25.88 Quite Low
Neurological Disease 1 13.04 Low Low
Neurodegenerative Disease 2 7.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although ataxin-1 and ataxin-2 interact physically and genetically [37.38], the knockout phenotypes of the respective genes show little overlap [16] with the caveat that innate and learned fear behaviors were not reported for Atxn1 ko mice.


ataxin-1 Binding (interact) of ataxin-2 associated with targeted disruption and anxiety disorder
1) Confidence 0.39 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2707006 Disease Relevance 1.10 Pain Relevance 0.17

General Comments

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