INT275464

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF69, MMP2) intracellular (ZNF69) DNA binding (ZNF69)
extracellular space (MMP2) peptidase activity (MMP2) extracellular region (MMP2)
Anatomy Link Frequency
HDFs 2
ZNF69 (Homo sapiens)
MMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 62 93.20 High High
Arthritis 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosarcoma 3 33.60 Quite Low
Cancer 10 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Metastasis 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Pathologic Processes 3 5.00 Very Low Very Low Very Low
Wrinkles 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
COS with 3–5 kDa exhibited the highest inhibitory effect on MMP-2 activity in HDFs, and protein expression of MMP-2 was also inhibited by COS with same molecular weight.
COS Negative_regulation (inhibited) of Gene_expression (expression) of MMP-2 in HDFs
1) Confidence 0.01 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2707034 Disease Relevance 0 Pain Relevance 0.05

General Comments

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