INT275540

Context Info Confidence 0.01 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.13 Pain Relevance 0.22

extracellular space (SELE) cell adhesion (SELE) plasma membrane (SELE)

SELE (Homo sapiens)

Pain Link Frequency Relevance Heat antagonist 19 95.20 Inflammation 49 90.84 substance P 1 56.16 fibrosis 3 38.44 cytokine 18 23.68 corticosteroid 13 5.00 chemokine 10 5.00 rheumatoid arthritis 6 5.00 metalloproteinase 5 5.00 agonist 5 5.00

Disease Link Frequency Relevance Heat Pulmonary Disease 107 98.84 Adhesions 7 98.68 Asthma 10 98.48 INFLAMMATION 47 90.84 Infection 5 68.24 Cystic Fibrosis 1 38.44 Disease 16 5.00 Stress 11 5.00 Nicotine Addiction 10 5.00 Rheumatoid Arthritis 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Another selectin inhibitor, the imidazole compound OC 229648, is under evaluation for treatment of COPD and asthma (Romano and Slee 2001).

Regulation (under) of Negative_regulation (inhibitor) of selectin associated with asthma and pulmonary disease

1) Confidence 0.01 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707155 Disease Relevance 1.13 Pain Relevance 0.22

General Comments

This test has worked.