INT275550

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.29
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand1, Hand2) DNA binding (Hand1, Hand2) nucleus (Hand1, Hand2)
transcription factor binding (Hand1, Hand2) nucleoplasm (Hand1) enzyme binding (Hand1)
Anatomy Link Frequency
skin 2
Hand1 (Mus musculus)
Hand2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 98.84 Very High Very High Very High
psoriasis 3 96.62 Very High Very High Very High
Inflammation 49 85.12 High High
rheumatoid arthritis 6 73.12 Quite High
corticosteroid 13 41.12 Quite Low
antagonist 19 18.64 Low Low
metalloproteinase 5 14.80 Low Low
chemokine 10 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Infliximab 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 3 96.62 Very High Very High Very High
Chronic Hepatitis 1 93.92 High High
Infection 5 92.32 High High
INFLAMMATION 47 85.12 High High
Repression 1 84.08 Quite High
Hepatitis 1 73.76 Quite High
Rheumatoid Arthritis 6 73.12 Quite High
Disease 16 71.84 Quite High
Pulmonary Disease 107 61.92 Quite High
Pneumonia 5 57.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clinical studies performed in patients with psoriasis showed that subcutaneous injections of IL-10 improved skin lesions and reduced the expression of Th1 cytokines (Asadullah et al 2003), thus suggesting an IL-10-induced shift from Th1 to Th2 immune response.
Th1 Positive_regulation (shift) of Localization (response) of Th2 in skin associated with psoriasis and cytokine
1) Confidence 0.00 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707155 Disease Relevance 1.29 Pain Relevance 0.46

General Comments

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