INT275552

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.28
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Anatomy Link Frequency
epithelial cells 3
macrophages 1
Tlr4 (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 36 81.36 Quite High
antagonist 38 75.28 Quite High
Infliximab 8 74.32 Quite High
Inflammation 98 69.52 Quite High
anakinra 4 57.92 Quite High
rheumatoid arthritis 12 53.84 Quite High
Etanercept 2 30.64 Quite Low
Adalimumab 2 26.52 Quite Low
psoriasis 6 20.36 Low Low
corticosteroid 26 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 214 92.56 High High
INFLAMMATION 94 69.52 Quite High
Nicotine Addiction 20 59.80 Quite High
Rheumatoid Arthritis 12 53.84 Quite High
Autoimmune Disease 2 48.12 Quite Low
Chronic Disease 2 47.44 Quite Low
Hypersensitivity 2 46.28 Quite Low
Infection 10 34.72 Quite Low
Psoriasis 6 20.36 Low Low
Disease 32 18.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cigarette smoke and lipopolysaccharide (LPS) stimulate macrophages and epithelial cells to produce interleukin-1 (IL-1), which in turn induces TNF-?
LPS Positive_regulation (stimulate) of in macrophages Gene_expression (produce) of IL-1 in epithelial cells
1) Confidence 0.00 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707155 Disease Relevance 0.64 Pain Relevance 0.29
Cigarette smoke and lipopolysaccharide (LPS) stimulate macrophages and epithelial cells to produce interleukin-1 (IL-1), which in turn induces TNF-?
LPS Positive_regulation (stimulate) of Gene_expression (produce) of IL-1 in epithelial cells
2) Confidence 0.00 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707155 Disease Relevance 0.64 Pain Relevance 0.29

General Comments

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