INT275639

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.87
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HNF4A) nucleoplasm (HNF4A) nucleus (HNF4A)
DNA binding (HNF4A) cytoplasm (HNF4A)
HNF4A (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 90.72 High High
Crohn's disease 80 72.68 Quite High
fibrosis 1 61.08 Quite High
ischemia 2 59.28 Quite High
Nicotine 7 45.20 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 84.72 Quite High
Colon Cancer 34 76.44 Quite High
Nicotine Addiction 97 73.60 Quite High
Disease 86 72.68 Quite High
Fibrosis 1 61.08 Quite High
Cv Unclassified Under Development 2 59.28 Quite High
Increased Venous Pressure Under Development 1 56.36 Quite High
Congenital Anomalies 3 51.04 Quite High
Apoptosis 3 27.52 Quite Low
Colitis 1 21.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin/TCF complex is required for proper transcriptional activity, we examined the possibility that Wnt-induced PLDs upregulation could enhance the association of ?
Positive_regulation (required) of TCF Spec (examined) Binding (complex) of
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920823 Disease Relevance 0.08 Pain Relevance 0
-catenin pathway, which ultimately results in an activation of the DNA bound TCF/LEF transcription factors.
Positive_regulation (activation) of TCF Binding (bound) of
2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2708910 Disease Relevance 0.79 Pain Relevance 0.21

General Comments

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