INT275746

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bax) endoplasmic reticulum (Bax) intracellular (Bax)
cytoplasm (Bax) cytosol (Bax) cell proliferation (Bax)
xn (Mus musculus)
Bax (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Potency 4 5.00 Very Low Very Low Very Low
vagus nerve 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 30 100.00 Very High Very High Very High
Death 8 99.08 Very High Very High Very High
Pheochromocytoma 2 89.56 High High
Disease 50 84.16 Quite High
Cognitive Disorder 8 81.32 Quite High
Diabetes Mellitus 36 13.44 Low Low
Insulin Resistance 10 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Parkinson's Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that HN protects against apoptosis by binding pro-apoptotic Bax, inhibiting its mitochondrial localization, and attenuating Bax-mediated apoptosis activation [2].
HN Binding (binding) of Bax associated with apoptosis
1) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709436 Disease Relevance 1.27 Pain Relevance 0
Once dimerized, HN directly interacts with a variety of pro-apoptotic proteins, including Bax-related proteins [2] and insulin-like growth factor binding protein-3 (IGFBP-3) [11].
HN Binding (interacts) of Bax-related associated with apoptosis
2) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709436 Disease Relevance 1.30 Pain Relevance 0

General Comments

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