INT27575

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Context Info
Confidence 0.45
First Reported 1989
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CEACAM1) plasma membrane (CEACAM1) molecular_function (CEACAM1)
CEACAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 67.20 Quite High
Pain 1 25.52 Quite Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 78 99.16 Very High Very High Very High
Metabolic Bone Disease 1 98.96 Very High Very High Very High
Cancer 12 97.16 Very High Very High Very High
Metastasis 5 95.32 Very High Very High Very High
Breast Disease 1 81.92 Quite High
Crohn's Disease 109 80.56 Quite High
Breast Cancer 2 75.00 Quite High
INFLAMMATION 24 67.20 Quite High
Skin Cancer 8 54.64 Quite High
Disease 40 53.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Circulating osteocalcin (BGP), the major noncollagenous bone protein, is elevated in patients with certain metabolic bone disease while its behavior in cancer patients, particularly those with bone metastases, is unclear.
Positive_regulation (elevated) of BGP associated with metabolic bone disease, cancer and metastasis
1) Confidence 0.45 Published 1989 Journal Cancer Invest. Section Abstract Doc Link 2630006 Disease Relevance 0.78 Pain Relevance 0
Consistent with increased transcript levels measured by microarrays, a marked up-regulation of CEACAM1 protein was seen in IBD when compared to normal controls (Figure 4A).
Positive_regulation (regulation) of CEACAM1 associated with inflammatory bowel disease
2) Confidence 0.30 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1188246 Disease Relevance 0.79 Pain Relevance 0.03

General Comments

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