INT275751

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Gpr83)
Anatomy Link Frequency
skeletal muscle 1
xn (Mus musculus)
Gpr83 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
vagus nerve 2 68.48 Quite High
Potency 4 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 90.56 High High
Apoptosis 30 88.12 High High
Insulin Resistance 10 24.16 Low Low
Diabetes Mellitus 36 22.80 Low Low
Disease 50 20.96 Low Low
Death 8 5.00 Very Low Very Low Very Low
Cognitive Disorder 8 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Parkinson's Disease 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Remarkably, centrally-administered HN dramatically increased GIR not only due to effects on HGP, but also through an increase in peripheral glucose uptake, demonstrating that HN is the first centrally-acting peptide to favorably modulate glucose uptake in skeletal muscle.
HN Positive_regulation (increased) of GIR in skeletal muscle
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709436 Disease Relevance 0.06 Pain Relevance 0.03
As expected, infusion of IGFBP-3 ICV led to a decrease in GIR, but both ICV HN and the non-BP3-binding HN analogue (F6AHN) increased GIR (P<0.05, Fig. 4C).
ICV HN Positive_regulation (increased) of GIR
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709436 Disease Relevance 0.18 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox