INT275754

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Igfbp3) extracellular region (Igfbp3) nucleus (Igfbp3)
xn (Mus musculus)
Igfbp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Potency 2 87.96 High High
vagus nerve 1 25.72 Quite Low
Somatostatin 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 1 96.60 Very High Very High Very High
Cognitive Disorder 4 95.96 Very High Very High Very High
Disease 25 83.48 Quite High
Amyloid Plaque 1 73.04 Quite High
Apoptosis 15 69.68 Quite High
Insulin Resistance 5 65.00 Quite High
Diabetes Mellitus 18 54.88 Quite High
Death 4 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A substitution of phenylalanine in the 6th position with alanine (F6A, F6AHN) alters the binding of HN to IGFBP-3 and we show here that this substitution significantly enhances its central effect on glucose metabolism.
Regulation (alters) of HN Binding (binding) of IGFBP-3
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709436 Disease Relevance 0.79 Pain Relevance 0.04

General Comments

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