INT275771

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prep) peptidase activity (Prep) nucleus (Prep)
cytoplasm (Prep)
Prep (Mus musculus)
Musd1 (Mus musculus)
Pain Link Frequency Relevance Heat
analgesia 8 79.68 Quite High
Enkephalin 4 50.00 Quite Low
tail-flick 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
antinociception 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, in case of Ala-Ala (2d), Pro-Ala (2e) or Ala-Pro (2f) combinations, the in vitro half-lives were practically the same (around 20 min) that may imply that the affinity of POP to Pro is somewhat higher than to Ala, especially when Pro is the preceding amino acid.
POP Binding (affinity) of Pro
1) Confidence 0.00 Published 2008 Journal The Open Medicinal Chemistry Journal Section Body Doc Link PMC2709471 Disease Relevance 0 Pain Relevance 0.08

General Comments

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